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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NSFL1C All Species: 26.06
Human Site: S145 Identified Species: 47.78
UniProt: Q9UNZ2 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNZ2 NP_057227.2 370 40573 S145 T K S P G E T S K P R P F A G
Chimpanzee Pan troglodytes XP_001154206 372 40798 S147 T K S P G E T S K P R P F A G
Rhesus Macaque Macaca mulatta XP_001113343 370 40568 S145 T K S P G E T S K P R P F A G
Dog Lupus familis XP_535083 412 46072 S188 L N E A T R A S G D N K S K S
Cat Felis silvestris
Mouse Mus musculus Q9CZ44 370 40691 S145 T K S P G E T S K P R P F A G
Rat Rattus norvegicus O35987 370 40661 S145 T K S P G E T S K P R P F A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513617 380 43203 V156 D E A A R T S V D G H K S K S
Chicken Gallus gallus Q5ZK10 369 40622 S144 A K S S G E S S K P K P F A G
Frog Xenopus laevis Q0P3R5 350 39530 Y126 S K S S G A F Y R A R T F T G
Zebra Danio Brachydanio rerio NP_001007447 372 40686 S146 G L G E S S K S K P F G G G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793278 394 42019 R181 S Q P R N T S R A F R G A G Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q7Y175 421 44978 P197 A V D R P V E P S R S A S T S
Baker's Yeast Sacchar. cerevisiae P34223 423 46969 A198 D E D H E M G A N R F T G R G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 99.7 41.5 N.A. 96.2 96.4 N.A. 44.7 88.1 42.9 72.3 N.A. N.A. N.A. N.A. 43.1
Protein Similarity: 100 99.4 100 60.1 N.A. 99.1 99.4 N.A. 65.7 94.8 61 84.6 N.A. N.A. N.A. N.A. 59.6
P-Site Identity: 100 100 100 6.6 N.A. 100 100 N.A. 0 73.3 40 26.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 6.6 N.A. 100 100 N.A. 20 86.6 53.3 26.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 27.5 25 N.A.
Protein Similarity: N.A. N.A. N.A. 45.6 42.5 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 8 16 0 8 8 8 8 8 0 8 8 47 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 0 16 0 0 0 0 0 8 8 0 0 0 0 0 % D
% Glu: 0 16 8 8 8 47 8 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 8 16 0 54 0 0 % F
% Gly: 8 0 8 0 54 0 8 0 8 8 0 16 16 16 70 % G
% His: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 54 0 0 0 0 8 0 54 0 8 16 0 16 0 % K
% Leu: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 8 0 0 0 8 0 8 0 0 0 0 % N
% Pro: 0 0 8 39 8 0 0 8 0 54 0 47 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 16 8 8 0 8 8 16 54 0 0 8 0 % R
% Ser: 16 0 54 16 8 8 24 62 8 0 8 0 24 0 24 % S
% Thr: 39 0 0 0 8 16 39 0 0 0 0 16 0 16 0 % T
% Val: 0 8 0 0 0 8 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _